Magnetic hyperthermia behaviour of Co and reduced GO nanocomposites
Author(s) -
Kakavand Anahita,
Sadrnezhaad Sayed Khatiboleslam
Publication year - 2020
Publication title -
micro and nano letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.25
H-Index - 31
ISSN - 1750-0443
DOI - 10.1049/mnl.2019.0272
Subject(s) - nanocomposite , hyperthermia , magnetic hyperthermia , materials science , composite material , nanotechnology , magnetic nanoparticles , nanoparticle , medicine
Co‐precipitation of CoCl 2 . 6H 2 O with graphene oxide (GO) and heating at 400°C for 4 h under hydrogen resulted in the construction of cobalt/reduced GO (Co/rGO) nanocomposite utilisable in magnetic thermal therapy. Field emission scanning electron microscopy, transmission electron microscopy, X‐ray photoelectron spectroscopy, vibrating sample magnetometry, thermogravimetric analysis/derivative thermogravimetry, and X‐ray diffraction methods characterised the samples. Time–temperature curves of the samples containing 30, 50, 70, and 100 µg ml −1 Co/rGO nanoparticles (NPs) suspended in phosphate‐buffered saline were determined at different specific heating rates. Magnetic‐field response of Co/rGO nanocomposites was better than CoNPs and GO. The biological behaviour of the powders was investigated by 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide assay. Co/rGO nanocomposites showed an acceptable biocompatibility behaviour, whereas the CoNPs demonstrated toxic conduct.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom