Open AccessAptamer and graphene‐based electrochemical biosensor for dopamine determination with high sensitivity and selectivity
Author(s) -
Jiao Luyang,
Lu Guangjian,
Zhang Chunxiao,
Yuan Yan,
Wang Junxiang,
Zhang Qunmei,
Li Pingfa
Publication year - 2013
Publication title -
micro and nano letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.25
H-Index - 31
ISSN - 1750-0443
DOI - 10.1049/mnl.2013.0626
Subject(s) - aptamer , graphene , biosensor , selectivity , sensitivity (control systems) , nanotechnology , materials science , chemistry , biology , biochemistry , electronic engineering , microbiology and biotechnology , engineering , catalysis
Dopamine is a kind of neurotransmitter. The abnormalities in dopamine metabolism may lead to various psychiatric and neurodegenerative diseases. Thus, fast and accurate detection of dopamine is urgently needed. Presented in this Letter is a convenient and cost‐effective electrochemical method for the detection of dopamine based on aptamer and graphene. The specific recognition between dopamine and the RNA aptamer allows high selectivity, and the excellent electronic properties of graphene nanosheets ensure the high sensitivity of this biosensor.