Open AccessSolvothermal‐assisted green synthesis of hybrid Chi‐Fe 3 O 4 nanocomposites: a potential antibacterial and antibiofilm material
Author(s) -
Senthilkumar Palanisamy,
Babu Sudhagar,
Jaishree Venkatachalam,
Joshua Stephen Kingsly,
Yaswant Govindaraj,
Ranjith Santhosh Kumar Devanesan Sanjeevi,
Nair Nithya S.
Publication year - 2020
Publication title -
iet nanobiotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.366
H-Index - 38
eISSN - 1751-875X
pISSN - 1751-8741
DOI - 10.1049/iet-nbt.2020.0056
Subject(s) - nanocomposite , antibacterial activity , materials science , transmission electron microscopy , fourier transform infrared spectroscopy , nanoparticle , nuclear chemistry , magnetite , spinel , nanotechnology , chemical engineering , analytical chemistry (journal) , chemistry , metallurgy , chromatography , bacteria , biology , engineering , genetics
In this present study, a hybrid Chi‐Fe 3 O 4 was prepared, characterised and evaluated for its antibacterial and antibiofilm potential against Staphylococcus aureus and Staphylococcus marcescens bacterial pathogens. Intense peak around 260 nm in the ultraviolet–visible spectrum specify the formation of magnetite nanoparticles. Spherical‐shaped particles with less agglomeration and particle size distribution of 3.78–46.40 nm were observed using transmission electron microscopy analysis and strong interaction of chitosan with the surface of magnetite nanoparticles was studied using field emission scanning microscopy (FESEM). X‐ray diffraction analysis exhibited the polycrystalline and spinel structure configuration of the nanocomposite. Presence of Fe and O, C and Cl elements were confirmed using energy dispersive X‐ray microanalysis. Fourier transform infrared spectroscopic analysis showed the reduction and formation of Chi‐Fe 3 O 4 nanocomposite. The antibacterial activity by deformation of the bacterial cell walls on treatment with Chi‐Fe 3 O 4 nanocomposite and its interaction was visualised using FESEM and the antibiofilm activity was determined using antibiofilm assay. In conclusion, this present study shows the green synthesis of Chi‐Fe 3 O 4 nanocomposite and evaluation of its antibacterial and antibiofilm potential, proving its significance in medical and biological applications