Open AccessEvolving nanotechnological trends in the management of mycotic keratitis
Author(s) -
Rai Mahendra,
Grupenmacher Alex,
Ingle Avinash P.,
Paralikar Priti,
Gupta Indarchand,
Alves Monica
Publication year - 2019
Publication title -
iet nanobiotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.366
H-Index - 38
eISSN - 1751-875X
pISSN - 1751-8741
DOI - 10.1049/iet-nbt.2018.5416
Subject(s) - keratitis , fungal keratitis , medicine , intensive care medicine , dermatology , corneal disease , cornea , ophthalmology
The alarming increase in global burden of various corneal diseases in general and mycotic keratitis in particular has raised up a major concern for its treatment. Mycotic keratitis is one of the most serious infections among the various ocular diseases. The proper diagnosis and effective treatment strategies remain a great challenge for ophthalmologists. The inefficacy and failure of conventional treatments have generated need to develop alternative approaches for the treatment of mycotic keratitis. Considering the promising applications of nanotechnology in biomedical area, it is believed that various nanomaterials can be effectively used in the management of mycotic keratitis. This review focuses on worldwide burden of various corneal diseases including mycotic keratitis and the role of nanotechnology in its treatment. In addition, safety and toxicological issues are also discussed.