Low‐temperature synthesis of hierarchical structures of copper oxide and their superior biological activity

In this work, the authors report a facile low‐temperature wet‐chemical route to prepare morphology‐tailored hierarchical structures (HS) of copper oxide. The preparation of copper oxide collides was carried out using varying concentrations of copper acetate and a reducing agent at a constant temperature of 50°C. The prepared HS of CuO were characterised by powdered X‐rays diffraction that indicates phase pure having monoclinic structures. The morphology was further confirmed by field‐emission scanning electron microscope. It reveals a difference in shape and size of copper oxide HS by changing the concentration of reactants. In order to evaluate the effect of H 2 O 2 on CuO NPs, the prepared CuO are modified by treatment with H 2 O 2 . In general trend, CuOH 2 O 2 collide showed enhanced protein kinase inhibition, antibacterial (maximum zone 16.34 mm against Staphylococcus aureus ) and antifungal activities in comparison to unmodified CuO collides. These results reveal that CuO HS exhibit antimicrobial properties and can be used as a potential candidate in pharmaceutical industries.