Open AccessBio‐inspired synthesis of silver nanoparticles from leaf extracts of Cleistanthus collinus (Roxb.): its potential antibacterial and anticancer activities
Author(s) -
Mohanta Yugal Kishore,
Panda Sujogya Kumar,
Syed Asad,
Ameen Fuad,
Bastia Akshaya Kumar,
Mohanta Tapan Kumar
Publication year - 2018
Publication title -
iet nanobiotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.366
H-Index - 38
eISSN - 1751-875X
pISSN - 1751-8741
DOI - 10.1049/iet-nbt.2017.0203
Subject(s) - silver nanoparticle , nuclear chemistry , antibacterial activity , chemistry , dynamic light scattering , fourier transform infrared spectroscopy , bacillus subtilis , nanoparticle , nanotechnology , materials science , bacteria , biology , chemical engineering , genetics , engineering
In this investigation, the biological synthesis method was adopted to synthesise silver nanoparticles (AgNPs) by using the leaf extracts of Cleistanthus collinus ( C. collinus ). This plant has traditionally been used to remove the harmful pest from the agriculture field. Leaf extract of C. collinus was used as bioreductant on the precursor solvent of AgNO 3 . The synthesised AgNPs were characterised by spectroscopic method such as UV–vis spectroscopy, attenuated total reflection Fourier transform infrared spectroscopy, dynamic light scattering and microscopic method by field‐emission scanning electron microscopy analysis. The AgNPs were studied for both antibacterial and antifungal activities and found to exhibit potential antibacterial activity against Bacillus subtilis , Staphylococcus aureus and Pseudomonas aeruginosa . The anticancer activity of AgNPs was screened against A‐431 osteosarcoma cell line by [3‐(4, 5‐dimetheylthiazol‐2)‐2, 5 diphenyl tetrazolium bromide] assay and the IC 50 value was found to be 91.05 ± 1.53 μg/ml. This trend of eco‐friendly stable synthesis of AgNPs could prove a better substitute for the chemical methods and offer greater opportunity to use these nanosilvers in agricultural and biomedical sectors.