Open AccessProduction, stabilisation and characterisation of silver nanoparticles coated with bioactive polymers pluronic F68, PVP and PVA
Author(s) -
Santos Carolina A.,
Balcão Victor M.,
Chaud Marco V.,
Seckler Marcelo Martins,
Rai Mahendra,
Vila Marta M.D.C.
Publication year - 2017
Publication title -
iet nanobiotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.366
H-Index - 38
eISSN - 1751-875X
pISSN - 1751-8741
DOI - 10.1049/iet-nbt.2016.0162
Subject(s) - polyvinylpyrrolidone , poloxamer , polyvinyl alcohol , nanoparticle , materials science , nanomedicine , polymer , silver nanoparticle , nanotechnology , stabiliser , antimicrobial , chemical engineering , biomolecule , nanobiotechnology , chemistry , organic chemistry , polymer chemistry , copolymer , engineering , composite material
The increasing and alarming panorama of bacterial infections and associated morbidities that occur during medical and hospital procedures makes the development of technologies that aid in controlling such bacterial infections of utmost importance. Recent studies have shown that formulations with metal nanoparticles exhibit good antibacterial properties against a broad spectrum of microorganisms. Moreover, it was demonstrated that some biologically active polymeric materials, when applied in combination with chemical antimicrobial agents, enhance the therapeutic action of the latter. The research effort entertained herein aimed at the physico‐chemical characterisation of silver nanoparticles obtained by chemical reduction, stabilised by bioactive polymers polyvinyl alcohol and polyvinylpyrrolidone, and further co‐stabilised by pluronic F68. Scanning electron microscopy images of the nanoparticles produced, coated with different stabilisers, have shown that the chemical nature of the stabilisation effect promoted incorporation of pluronic in the nanoparticles and was closely related to an increase in the silver concentration in the nanoparticle samples obtained via energy‐dispersive X‐ray spectroscopy. The study described herein also shows that the nature of the stabiliser favours the interaction of pluronic F68 with samples containing silver nanoparticles.