Open AccessInfluence of ball milling on the particle size and antimicrobial properties of Tridax procumbens leaf nanoparticles
Author(s) -
Karthik Subramani,
Suriyaprabha Rangaraj,
Balu Kolathupalayam Shanmugam,
Manivasakan Palanisamy,
Rajendran Venkatachalam
Publication year - 2017
Publication title -
iet nanobiotechnology
Language(s) - English
Resource type - Journals
ISSN - 1751-875X
DOI - 10.1049/iet-nbt.2016.0028
Subject(s) - particle size , antimicrobial , nanoparticle , crystallinity , fourier transform infrared spectroscopy , materials science , dynamic light scattering , ball mill , scanning electron microscope , nanotechnology , nuclear chemistry , chemical engineering , chemistry , organic chemistry , composite material , engineering
The herbal nanoparticles were prepared from shade dried Tridax procumbens plant leaves employing ball milling technique using different process parameters, like ball ratio/size and milling time. The obtained nanoparticles were comprehensively characterised using X‐ray diffraction, Fourier transform infrared spectroscopy, UV–visible spectroscopy, dynamic light scattering, scanning electron microscopy and antimicrobial analysis techniques. The crystallinity of the nanoparticles was retained without altering even though the particle size changes due to milling periods. The antibacterial activities of the prepared herbal nanoparticles against Staphylococcus aureus and Escherichia coli were explored to understand the influence of particle size on antimicrobial activities and their functional properties. The increase in ball ratio and milling time periods leads to a decrease in nanoparticle size from 114 to 45 nm which in turn increases the antimicrobial activities. The above study confirms that antimicrobial activity relies on nanoparticle size. The observed knowledge on influence of particle size on antimicrobial activities will help to optimise the production of potential herbal nanoparticles for different biomedical applications.