Open AccessIonic selectivity of nystatin A1 confined in nanoporous track‐etched polymer membrane
Author(s) -
Balme Sébastien,
Thiele Daniela,
Kraszewski Sebastian,
Picaud Fabien,
Janot JeanMarc,
Déjardin Philippe
Publication year - 2014
Publication title -
iet nanobiotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.366
H-Index - 38
eISSN - 1751-875X
pISSN - 1751-8741
DOI - 10.1049/iet-nbt.2013.0014
Subject(s) - nanopore , membrane , ionic bonding , selectivity , nanoporous , polymer , materials science , permeation , nanotechnology , chemistry , chemical engineering , ion , organic chemistry , composite material , biochemistry , engineering , catalysis
The hybrid biological/polymeric solid‐state nanopore membrane offers several opportunities to combine the advantage of biological channel (selectivity) and material (robustness). Based on this technology, the challenge is to obtain selective ionic exchange membranes, with no energy intake. The direct insertion of an ionic channel inside a nanopore should be a promise solution. Here, the authors report a hybrid nanopore based on nystatin A1 confinement in commercial nanopore membrane. Ionic transport and selectivity studies show that the hybrid nanopores exhibit mainly an anionic behaviour, on the contrary to biological conditions. However, the order of magnitude between the different ratios of permeation of several cationic species is retained even if the blocking of divalent cation is not totally proved.