Open AccessAutomatic detection of acute lymphoblastic leukaemia based on extending the multifractal features
Author(s) -
Abbasi Mohamadreza,
Kermani Saeed,
Tajebib Ardeshir,
Moradi Amin Morteza,
Abbasi Manije
Publication year - 2020
Publication title -
iet image processing
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.401
H-Index - 45
eISSN - 1751-9667
pISSN - 1751-9659
DOI - 10.1049/iet-ipr.2018.5910
Subject(s) - pattern recognition (psychology) , artificial intelligence , overfitting , fractal dimension , multifractal system , chaotic , feature vector , principal component analysis , support vector machine , box counting , feature (linguistics) , mathematics , multiclass classification , binary number , dimension (graph theory) , contextual image classification , computer science , fractal , dimensionality reduction , fractal analysis , image (mathematics) , artificial neural network , mathematical analysis , linguistics , philosophy , arithmetic , pure mathematics
The main purpose of this study is to introduce a new species of features to improve the diagnosis efficiency of acute lymphoblastic leukaemia from microscopic images. First, the authors segmented nuclei by the k ‐means and watershed algorithms. They extracted three sets of geometrical, statistical, and chaotic features from nuclei images. Six chaotic features were extracted by calculating the fractal dimension from five sub‐images driven from the nuclei images, with their grey levels being modified. The authors classified the images into binary and multiclass types via the support vector machine algorithm. They conducted principal component analysis for dimensional reduction of feature space and then evaluated the proposed algorithm for the overfitting problem. The obtained overall results represent 99% accuracy, 99% specificity, and 97% sensitivity values in the classification of six‐cell groups. The difference between the train and test errors was <3%, which proves that the classification performance had improved by using the multifractal features.