Open AccessMultimodal non‐rigid registration methods based on local variability measures in computed tomography and magnetic resonance brain images
Author(s) -
Reducindo Isnardo,
MejiaRodriguez Aldo R.,
ArceSantana Edgar R.,
CamposDelgado Daniel U.,
ViguerasGomez Flavio,
Scalco Elisa,
Bianchi Anna M.,
Cattaneo Giovanni M.,
Rizzo Giovanna
Publication year - 2014
Publication title -
iet image processing
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.401
H-Index - 45
eISSN - 1751-9667
pISSN - 1751-9659
DOI - 10.1049/iet-ipr.2013.0705
Subject(s) - image registration , parametric statistics , computer science , maxima and minima , deformation (meteorology) , magnetic resonance imaging , optical flow , artificial intelligence , computer vision , tomography , entropy (arrow of time) , mathematics , physics , optics , mathematical analysis , radiology , medicine , statistics , quantum mechanics , meteorology , image (mathematics)
This paper presents a novel non‐rigid multimodal registration method that relies on three basic steps: first, an initial approximation of the deformation field is obtained by a parametric registration technique based on particle filtering; second, an intensity mapping based on local variability measures (LVM) is applied over the two images in order to overcome the multimodal restriction between them; and third, an optical flow method is used in an iterative way to find the remaining displacements of the deformation field. Hence the new methodology offers a solution for multimodal NRR by a quadratic optimisation over a convex surface, which allows independent motion of each pixel, in contrast to methods that parameterise the deformation space. To evaluate the proposed method, a set of magnetic resonance/computed tomography clinical studies (pre‐ and post‐radiotherapy treatment) of three patients with cerebral tumour deformations of the brain structures was employed. The resulting registration was evaluated both qualitatively and quantitatively by standard indices of correspondence over anatomical structures of interest in radiotherapy (brain, tumour and cerebral ventricles). These results showed that one of the proposed LVM (entropy) offers a superior performance in estimating the non‐rigid deformation field.