Open AccessNetwork analysis through the use of joint‐distribution entropy on EEG recordings of MCI patients during a visual short‐term memory binding task
Author(s) -
Josefsson Alexandra,
Ibáñez Agustín,
Parra Mario,
Escudero Javier
Publication year - 2019
Publication title -
healthcare technology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.45
H-Index - 19
ISSN - 2053-3713
DOI - 10.1049/htl.2018.5060
Subject(s) - electroencephalography , brain activity and meditation , context (archaeology) , computer science , cognition , neuroscience , artificial intelligence , psychology , paleontology , biology
The early diagnosis of Alzheimer's disease (AD) is particularly challenging. Mild cognitive impairment (MCI) has been linked to AD and electroencephalogram (EEG) recordings are able to measure brain activity directly with high temporal resolution. In this context, with appropriate processing, the EEG recordings can be used to construct a graph representative of brain functional connectivity. This work studies a functional network created from a non‐linear measure of coupling of beta‐filtered EEG recordings during a short‐term memory binding task. It shows that the values of the small‐world characteristic and eccentricity are, respectively, lower and higher in MCI patients than in controls. The results show how MCI leads to EEG functional connectivity changes. They expect that the network differences between MCIs and control subjects could be used to gain insight into the early stages of AD.