CMOS‐based implantable glucose monitoring device with improved performance and reduced invasiveness | Zendy

Kawamura T. | Zendy; Masuda K. | Zendy; Hirai T. | Zendy; Ohta Y. | Zendy; Motoyama M. | Zendy; Takehara H. | Zendy; Noda T. | Zendy; Sasagawa K. | Zendy; Tokuda T. | Zendy; Okitsu T. | Zendy; Takeuchi S. | Zendy; Ohta J. | Zendy

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CMOS‐based implantable glucose monitoring device with improved performance and reduced invasiveness

Author(s) -

Kawamura T.,

Masuda K.,

Hirai T.,

Ohta Y.,

Motoyama M.,

Takehara H.,

Noda T.,

Sasagawa K.,

Tokuda T.,

Okitsu T.,

Takeuchi S.,

Ohta J.

Publication year - 2015

Publication title -

electronics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.375

H-Index - 146

eISSN - 1350-911X

pISSN - 0013-5194

DOI - 10.1049/el.2015.0612

Subject(s) - cmos , sensitivity (control systems) , biomedical engineering , reduction (mathematics) , electronic engineering , materials science , optoelectronics , engineering , geometry , mathematics

An implantable glucose monitoring device based on a CMOS line sensor combined with a glucose‐responsive fluorescent hydrogel is developed. An implantable glucose monitoring device with sufficient sensitivity and response time is realised, which is an improvement over the authors' previous proof‐of‐concept device. A reduction of the sensor size made the device diameter injectable with a commercially available 16‐gauge syringe needle. The sensor's performance was confirmed through both in vitro and in vivo experiments.

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