Rapid electronic prediction of gene expression regulation in bacterial cells | Zendy

Alam S. | Zendy; Lai E.MK. | Zendy; Young J. | Zendy; Hasan S.M.R. | Zendy

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Rapid electronic prediction of gene expression regulation in bacterial cells

Author(s) -

Alam S.,

Lai E.MK.,

Young J.,

Hasan S.M.R.

Publication year - 2014

Publication title -

electronics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.375

H-Index - 146

ISSN - 1350-911X

DOI - 10.1049/el.2014.2144

Subject(s) - escherichia coli , gene expression , gene , similarity (geometry) , biological system , microbiology and biotechnology , biology , expression (computer science) , short circuit , microsecond , computational biology , computer science , engineering , physics , genetics , artificial intelligence , electrical engineering , voltage , astronomy , image (mathematics) , programming language

A cytomorphic circuit that can mimic gene expression regulation mechanisms is presented. It is shown that this circuit can efficiently predict the cellular response of the bacterium Escherichia coli in real time. The simulation outputs of the circuit are compared with biological experimental results. The significant similarity between these results shows that the circuit can be used to predict cellular malfunctioning within microseconds.

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