Open AccessRapid electronic prediction of gene expression regulation in bacterial cells
Author(s) -
Alam S.,
Lai E.MK.,
Young J.,
Hasan S.M.R.
Publication year - 2014
Publication title -
electronics letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.375
H-Index - 146
ISSN - 1350-911X
DOI - 10.1049/el.2014.2144
Subject(s) - escherichia coli , gene expression , gene , similarity (geometry) , biological system , microbiology and biotechnology , biology , expression (computer science) , short circuit , microsecond , computational biology , computer science , engineering , physics , genetics , artificial intelligence , electrical engineering , voltage , astronomy , image (mathematics) , programming language
A cytomorphic circuit that can mimic gene expression regulation mechanisms is presented. It is shown that this circuit can efficiently predict the cellular response of the bacterium Escherichia coli in real time. The simulation outputs of the circuit are compared with biological experimental results. The significant similarity between these results shows that the circuit can be used to predict cellular malfunctioning within microseconds.