Open AccessAn optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip
Author(s) -
Saha Basudev,
Majumder Mukta
Publication year - 2021
Publication title -
iet computers and digital techniques
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.219
H-Index - 46
ISSN - 1751-861X
DOI - 10.1049/cdt2.12004
Subject(s) - biochip , tree traversal , microfluidics , graph traversal , control reconfiguration , computer science , fault detection and isolation , embedded system , digital microfluidics , computer hardware , engineering , nanotechnology , algorithm , artificial intelligence , voltage , materials science , electrical engineering , electrowetting , actuator
Conventional biomedical analysers are replaced by digital microfluidic biochips and they are adequate to integrate different biomedical functions, essential for diverse bioassay operations. From the last decade, microfluidic biochips are getting plenty of acceptances in the field of miscellaneous healthcare sectors like DNA analysis, drug discovery and clinical diagnosis. These devices are also bearing a vital role in the area of safety critical applications such as food safety testing, air quality monitoring etc. As these devices are used in safety critical applications, clinical diagnosis and real‐time biomolecular assay operations, these must have properties like precision, reliability and robustness. To accept it for discriminating purposes, the microfluidic device must endorse its preciseness and strength by following sublime testing strategy. Here, an optimized droplet traversal technique is proposed to investigate the multiple defective electrodes of a digital microfluidic biochip by embedding boundary cum row traversal and KNIGHT traversal procedure (based on the famous Knight Tour Problem). The proposed approach also enumerates the traversal time for a fault‐free biochip. In addition to identifying the faulty electrodes, a Module Sequencing Graph based reconfiguration technique is proposed here to reinstate the device for normal bioassay operation.