Open AccessThe fallacy of behavioral phenotyping without standardisation
Author(s) -
Van Der Staay F. J.,
Steckler T.
Publication year - 2002
Publication title -
genes, brain and behavior
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.315
H-Index - 91
eISSN - 1601-183X
pISSN - 1601-1848
DOI - 10.1046/j.1601-1848.2001.00007.x
Subject(s) - mutant , neuroscientist , fallacy , task (project management) , behavioral modeling , process (computing) , mutation , behavioral economics , psychology , computational biology , neuroscience , computer science , biology , genetics , artificial intelligence , engineering , economics , gene , systems engineering , finance , operating system , myelin , philosophy , epistemology , oligodendrocyte , central nervous system
Behavioral phenotyping of mutant mice is a new and challenging task for the behavioral neuroscientist. Therefore, standardisation of the experimental conditions is required to permit comparisons between the results of experiments within and between laboratories. Once mutation‐induced behavioral changes have been identified, phenotyping of mouse mutants should be performed along a systematic trajectory, which allows for an in‐depth characterisation of the mutant under investigation.