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Sun protection factor determination in vivo using a single exposure on sunscreen‐protected skin
Author(s) -
Diffey Brian L.
Publication year - 2003
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1046/j.1600-0781.2003.00057.x
Subject(s) - sun protection factor , sun protection , sunscreening agents , statistics , cohort , medicine , toxicology , mathematics , dermatology , skin cancer , biology , cancer
Background: Determining sunscreen sun protection factors (SPFs) in a cohort of volunteers, particularly on products designed to provide high levels of protection, can be time‐consuming. The conventional approach is to administer to each subject a series of exposures (normally between five and seven) on their sunscreen‐protected skin. Method: A method, based on Gaussian statistics, is proposed that requires just a single exposure on the sunscreen‐protected skin in volunteers to arrive at a reliable estimate of the mean SPF of a test product. Results/Conclusion: The method is shown to yield an estimate of a product's mean SPF that is comparable, or better, in accuracy to estimates obtained by conventional multi‐exposure testing.