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Long‐term effects of soybean protease inhibitors on digestive enzymes, survival and learning abilities of honeybees
Author(s) -
PhamDelègue MinhHà,
Girard Cécile,
Métayer Martine,
PicardNizou AnneLorraine,
Hennequet Christelle,
Pons Odile,
Jouanin Lise
Publication year - 2000
Publication title -
entomologia experimentalis et applicata
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.765
H-Index - 83
eISSN - 1570-7458
pISSN - 0013-8703
DOI - 10.1046/j.1570-7458.2000.00637.x
Subject(s) - biology , ingestion , protease , digestive enzyme , kunitz sti protease inhibitor , serine protease , trypsin inhibitor , protease inhibitor (pharmacology) , enzyme , foraging , insect , hymenoptera , biochemistry , botany , trypsin , zoology , amylase , immunology , ecology , human immunodeficiency virus (hiv) , antiretroviral therapy , viral load
We have investigated the effects of long‐term ingestion of two serine proteinase inhibitors (PIs), the Kunitz Soybean trypsin inhibitor (SBTI) and the Bowman‐Birk inhibitor (BBI) on survival, learning abilities involved in the foraging behaviour, and digestive physiology of the honeybee ( Apis mellifera L ., Hymenoptera). A threshold‐dose was established, above which adverse effects of long‐term ingestion of the PIs tested are to be expected. The experiments reported herein could be extended to other PIs or gene products used to confer insect resistance, and be part of a general procedure used to assess the innocuousness of transgenic melliferous plants to honeybees.