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The Effect of Kidney Transplant on Cardiac Function: An Echocardiographic Perspective
Author(s) -
SahagúnSánchez Guillermo,
EspinolaZavaleta Nilda,
LafraguaContreras Magdalena,
Chávez Pedro Yánac,
GómezNúñez Nelly,
Keirns Candace,
RomeroCardenas Angel,
PérezGrovas Héctor,
Acosta Jaime Herrera,
VargasBarrón Jesús
Publication year - 2001
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1046/j.1540-8175.2001.00457.x
Subject(s) - medicine , cardiology , ejection fraction , coronary artery disease , diastole , perfusion , dobutamine , kidney disease , left ventricular hypertrophy , heart failure , muscle hypertrophy , kidney transplantation , kidney , hemodynamics , blood pressure
Kidney transplant (KT) resolves many of the cardiac abnormalities associated with chronic kidney failure (CKF). This study analyzed cardiac alterations of kidney failure and their modification with transplant. Thirteen patients in CKF underwent conventional echocardiograms, dobutamine stress echocardiograms, and injection of contrast to examine perfusion before KT and 3 months after transplant. Nine patients had evidence of left ventricular hypertrophy and six had evidence of diastolic dysfunction. Wall thickness, left ventricular mass, and mass index diminished after KT; only two patients continued to manifest hypertrophy. Left ventricular systolic diameters and volumes diminished at 3 months, and diastolic diameters after 4 months. Left ventricular fractional shortening and ejection fraction increased 3 months after transplant. At the end of the study, only two patients continued to show diastolic dysfunction. Dobutamine echocardiograms showed no segmental wall‐movement abnormalities. Myocardial perfusion was normal before and after transplant. The results suggest that KT diminishes hypertrophy and improves left ventricular systolic and diastolic function. Echocardiography provides valuable information for detection and follow‐up of cardiac abnormalities in patients with kidney disease. Evaluation of segmental wall movement and myocardial perfusion aid in demonstrating that our studied patients with CKF had no indirect signs of coronary artery disease.