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Spontaneous T Wave Alternans in a Patient with Brugada Syndrome—Responses to Intravenous Administration of Class I Antiarrhythmic Drug, Glucose Tolerance Test, and Atrial Pacing
Author(s) -
NISHIZAKI MITSUHIRO,
FUJII HIROYUKI,
SAKURADA HARUMIZU,
KIMURA AKINORI,
HIRAOKA MASAYASU
Publication year - 2005
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1046/j.1540-8167.2004.40411.x
Subject(s) - medicine , cardiology , t wave alternans , brugada syndrome , electrocardiography , anesthesia , bundle branch block , sudden cardiac death
A 43‐year‐old man with an episode of syncope showed ECG patterns of coved‐type ST elevation in leads V1–V3 and right bundle branch block pattern. The patient had spontaneous T wave alternans at baseline, and T wave alternans diminished with distinct development of ST elevation after administration of Na + channel blocker, and during oral glucose load and atrial pacing. Na + channel mutation may contribute to the genesis of his ECG changes.