Spontaneous T Wave Alternans in a Patient with Brugada Syndrome—Responses to Intravenous Administration of Class I Antiarrhythmic Drug, Glucose Tolerance Test, and Atrial Pacing | Zendy

NISHIZAKI MITSUHIRO | Zendy; FUJII HIROYUKI | Zendy; SAKURADA HARUMIZU | Zendy; KIMURA AKINORI | Zendy; HIRAOKA MASAYASU | Zendy

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Spontaneous T Wave Alternans in a Patient with Brugada Syndrome—Responses to Intravenous Administration of Class I Antiarrhythmic Drug, Glucose Tolerance Test, and Atrial Pacing

Author(s) -

NISHIZAKI MITSUHIRO,

FUJII HIROYUKI,

SAKURADA HARUMIZU,

KIMURA AKINORI,

HIRAOKA MASAYASU

Publication year - 2005

Publication title -

journal of cardiovascular electrophysiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.193

H-Index - 138

eISSN - 1540-8167

pISSN - 1045-3873

DOI - 10.1046/j.1540-8167.2004.40411.x

Subject(s) - medicine , cardiology , t wave alternans , brugada syndrome , electrocardiography , anesthesia , bundle branch block , sudden cardiac death

A 43‐year‐old man with an episode of syncope showed ECG patterns of coved‐type ST elevation in leads V1–V3 and right bundle branch block pattern. The patient had spontaneous T wave alternans at baseline, and T wave alternans diminished with distinct development of ST elevation after administration of Na + channel blocker, and during oral glucose load and atrial pacing. Na + channel mutation may contribute to the genesis of his ECG changes.

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