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An Autopsy Case of Brugada Syndrome with Significant Lesions in the Sinus Node
Author(s) -
MORIMOTO SHINICHIRO,
UEMURA AKIHISA,
HISHIDA HITOSHI
Publication year - 2005
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1046/j.1540-8167.2004.40378.x
Subject(s) - medicine , brugada syndrome , fibrosis , cardiology , atrophy , autopsy , ventricle , muscle hypertrophy , sinus (botany) , endocardium , ventricular outflow tract , anatomy , botany , biology , genus
A 30‐year‐old man with Brugada syndrome died suddenly. The heart weighed 380 g. The left ventricular wall showed mild thickening, and marked fatty tissue deposition was noted in the right ventricular outflow tract. Neither ventricle was enlarged. Contraction band necrosis was diffuse in both ventricles. In the ventricles no cardiac muscle cell hypertrophy or atrophy, or significant interstitial fibrosis was observed. In the sinus node the number of nodal cells was reduced by half, with fatty tissue and fibrosis prominent. But no lesions were evident in the right bundle branch.