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Infant Case with a Malignant Form of Brugada Syndrome
Author(s) -
SUZUKI HIROSHI,
TORIGOE KATSUMI,
NUMATA OSAMU,
YAZAKI SATOSHI
Publication year - 2000
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1046/j.1540-8167.2000.01277.x
Subject(s) - medicine , brugada syndrome , ventricular fibrillation , ventricular tachycardia , cardiology , antagonist , agonist , implantable cardioverter defibrillator , incidence (geometry) , anesthesia , tachycardia , receptor , physics , optics
Infant with Brugada Syndrome. We report a 6‐nionth‐old Japanese infant with a malignant form of Brugada syndrome, who had frequent episodes of ventricular fibriitation (VF) and nonsustained polymorphic ventricular tachycardia (VT). To the best of our knowledge, this infant is the youngest patient reported to have Brugada syndrome. Continuous infusion of a β‐adrenergic agonist and intravenous injection of a parasympathetic antagonist suppressed the electrical storm of polymorphic VT and VF. Combined oral administration of a β 1 ‐adrenergic agonist, a parasympathetic antagonist, and quinidine has successfully suppressed recurrences of VT or VF for 6 months, and the combination may have the potential to decrease the incidence of VT or VF as an adjunctive therapy with prophylactic placement of an implantable cardioverter defibrillator.