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Use of percutaneous radial artery catheter for peripheral blood progenitor cell collection in pediatric patients
Author(s) -
Bambi Franco,
Fontanazza Silvia,
Messeri Andrea,
Lippi Alma,
Tucci Fabio,
Tamburini Angela,
Tintori Veronica,
Casini Tommaso,
Lacitignola Laura,
Tondo Annalisa,
Veltroni Marinella,
Bernini Gabriella,
Faulkner Lawrence B.
Publication year - 2003
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.2003.00292.x
Subject(s) - medicine , catheter , percutaneous , radial artery , surgery , anesthesia , blood flow , leukapheresis , peripheral , artery , cardiology , stem cell , biology , cd34 , genetics
BACKGROUND : Leukapheresis procedures require adequate flow rates, which in children may frequently involve invasive vascular access placement. STUDY DESIGN AND METHODS : A minimally invasive peripheral radial artery catheter was used for drawing blood in 85 leukapheresis procedures performed in 33 pediatric patients. Blood return to the patients was provided by either a central Broviac‐type catheter or a peripheral venous access. The patients' age range was 1 to 18 years (median, 9.5) and the weight range was 9 to 73 kg (median, 29 kg). Vasocan Braunüle Luer Lock IV cannulas (22 gauge in 78 and 20 gauge in 7) were placed percutaneously under local anesthesia, and in 8 patients, catheter placement was carried out during general anesthesia for other procedures. A continuous flow cell separator was used in all cases (Fresenius AS104 in 23 and AS204 in 62). RESULTS : Flow rates ranged from 18 to 45 mL per minute, the mean number of total blood volumes processed was 2.07 (range, 0.51‐2.51), and the mean duration of the procedures was 150 minutes (range, 90‐260). The 22‐gauge cannulas provided adequate flow rates independently of patient age and weight. No significant thrombotic, embolic, hemorrhagic, ischemic, or infectious complications were observed. CONCLUSION : Peripheral radial artery catheters are safe, are minimally invasive, and provide steady, high‐flow rates, and they should be considered for patients requiring leukapheresis and lacking a suitable vascular access for drawing blood.