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Evaluation of monoclonal anti‐glycophorin B as an unusual anti‐S
Author(s) -
Hemming N.J.,
Reid M.E.
Publication year - 1994
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1994.34494233582.x
Subject(s) - glycophorin , monoclonal antibody , monoclonal , microbiology and biotechnology , red blood cell , chemistry , antibody , serology , phenotype , virology , biology , immunology , antigen , biochemistry , gene
Background : Monoclonal antibody 148 is a murine monoclonal anti‐ glycophorin B that preferentially reacts with S+ human red cells. Study Design and Methods : Serologic and immunochemical studies were performed using red cells with various phenotypes. Results : These studies reveal that this monoclonal antibody is unusual in that it fails to agglutinate S+ TSEN+ red cells and agglutinates S‐ St(a+) and S‐ Dantu+ red cells. Conclusion : These results allow the prediction of the glycophorin composition of GP.Hop (Mi.IV) red cells.