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Transfusion and second malignancy
Author(s) -
Ford C.D.,
Gillette J.W.,
Handrahan D.L.,
Koehler C.S.
Publication year - 1994
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1994.34194098607.x
Subject(s) - malignancy , perioperative , medicine , blood transfusion , cancer , lung cancer , surgery , intensive care medicine
BACKGROUND: Perioperative blood transfusion has been reported to cause a variety of immunosuppressive effects, including increased rates of malignancy recurrence. The effect of perioperative transfusion on second malignancy risk has not previously been investigated. STUDY DESIGN AND METHODS: Second malignancy risk was evaluated in 1053 patients previously operated upon for colon cancer, and these findings are related to perioperative transfusion history. RESULTS: Transfusion history did not relate to the probability of a patient's remaining free of second malignancy. CONCLUSION: An increased risk of total or second malignancies (with the possible exception of lung cancer) was not associated with transfusion.