Premium
Rh phenotypes of Chinese blood donors in Hong Kong, with special reference to weak D antigens
Author(s) -
Mak K.H.,
Yan K.F.,
Cheng S.S.,
Yuen M.Y.
Publication year - 1993
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1993.33493242645.x
Subject(s) - phenotype , antigen , medicine , blood group antigens , immunology , biology , genetics , gene
Among Hong Kong Chinese blood donors, 99.71 percent were found to be D+. Of these, 55.02 percent were of the phenotype CCDee. The Du phenotype was found to be present in 0.016 percent. Among the 0.27 percent who were apparently D‐, 0.079 percent were of the Del phenotype, while the remaining 0.19 percent were “true D‐,” as defined by a nonreactive eluate obtained by an adsorption and elution procedure using anti‐D. The ccdee phenotype constitutes 56.77 percent of the “apparent D‐” and 80.24 percent of the true D‐. Data show that anti‐D rarely occurs in Hong Kong Chinese, and it is postulated that this could be due to the presence of a very weak form of the D antigen among many of those who appear to be D‐.