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HLA, GM, KM, and Diego blood group typing of Chippewa Indians
Author(s) -
Lee T. D.,
Zhao T. M.,
Chow M. P.,
Lee G.
Publication year - 1990
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1990.30891020334.x
Subject(s) - typing , tribe , human leukocyte antigen , allotype , ethnic community , population , abo blood group system , biology , ethnic group , immunology , hla a , demography , antigen , medicine , genetics , anthropology , sociology
This is the first report characterizing HLA antigen distribution in North American Indians of the Chippewa tribe. One hundred seventy‐four Chippewa from Minnesota underwent HLA‐A,B,C,DR, and DQ typing in a search for a single unrelated bone marrow donor. The high matching rate of this successful search is attributed to homozygosity and the extreme frequency of certain antigens in this small ethnic community. It is emphasized that smaller donor pools are required in searches within a minority population. GM and KM allotype typing as well as blood group Diego typing show patterns similar to those reported in other North American Indian groups.