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Autoimmune hemolytic anemia caused by a cold agglutinin with a new specificity (anti‐Ju)
Author(s) -
Göttsche B.,
Salama A.,
MuellerEckhardt C.
Publication year - 1990
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1990.30390194350.x
Subject(s) - cold agglutinin , cold agglutinin disease , autoimmune hemolytic anemia , autoantibody , antibody , immunology , neuraminidase , hemolytic anemia , coombs test , medicine , anemia , virus
A cold autoantibody detected in the serum of a patient with chronic idiopathic cold agglutinin disease and hemolytic anemia is described. The antibody reacted with adult as well as with cord red cells, and its reactivity was strongly diminished by treatment of the cells with neuraminidase and to a lesser degree by treatment with protease. Thus, the specificity of the antibody is distinct from those of all cold antibodies yet described.