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Unusual suppression of Kell system antigens in a healthy blood donor
Author(s) -
Norman P. C.,
Daniels G. L.
Publication year - 1988
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1988.28588337337.x
Subject(s) - phenotype , antigen , immunology , red cell , red blood cell , medicine , microbiology and biotechnology , biology , genetics , gene
Red cells of a Kp(a+) donor, ascertained as a result of screening donor red cell units with anti‐Kp a , reacted only very weakly with anti‐Kp b and demonstrated weakened expression of various other Kell and para‐ Kell antigens. Family studies revealed a Kp(a+) sister with similarly weakened expression of Kp b and other Kell and para‐Kell antigens. Red cell morphology was normal in both of these individuals. This phenotype is different from any previously reported and is named the Allen phenotype.