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Radiolabeled red cell viability
Author(s) -
Marcus C.S.,
Myhre B.A.,
Angulo M.C.,
Salk R.D.,
Essex C.E.,
Demianew S.H.
Publication year - 1987
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1987.27587320537.x
Subject(s) - viability assay , medicine , chemistry , cell , biochemistry
The authors developed a double in vivo crossmatch method using 2 to 3 ml of potential donor blood labeled with either 400 microCi of 99mTc or 30 microCi of 111In‐oxine. Data are presented for 19 crossmatches on nine patients, using one blood specimen labeled with 99m Tc or two specimens, one labeled with 99m Tc and the other with 111 In. Normal values are given for standardization purposes. This method appears to have advantages over earlier in vivo crossmatch techniques using 51 Cr‐ labeled RBCs. These advantages include the rapidity with which the in vivo crossmatch may be repeated, the ready availability of 99m Tc and 111In‐oxine, and the lower radiation absorbed doses with the shorter‐ lived radionuclides.