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The association of anti‐P and early abortion
Author(s) -
Shirey R. Sue,
Ness P. M.,
Kickler T. S.,
Rock J. A.,
Callan N. A.,
Schlaff W. D.,
Niebyl J.
Publication year - 1987
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1987.27287150197.x
Subject(s) - abortion , plasmapheresis , titer , serology , pregnancy , medicine , obstetrics , gynecology , antibody , immunology , biology , genetics
The current report details the serologic findings in a case reported previously of a P1k woman, para 0 gravida 13, who was treated during her fourteenth pregnancy with plasmapheresis to reduce the anti‐P titer. These studies suggest that anti‐P can induce early abortion in Pk women and that the abortions are immunologically mediated. Further, this case supports the disputed proposal that the anti‐P component of anti‐PP1Pk is responsible for pregnancy loss in p women.