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Hepatitis B core antibody (anti‐HBc) in blood donors in the United States: implications for surrogate testing programs
Author(s) -
KLINE W.E.,
BOWMAN R.J.,
MCCURDY K.K. ENNIS,
O'MALLEY J.P.,
SANDLER S.G.
Publication year - 1987
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1987.27187121486.x
Subject(s) - medicine , blood donations , antibody , blood donor , hepatitis b , blood units , immunology , hepatitis , virology , blood transfusion
In order to evaluate the operational implications of excluding donated blood with antibody to hepatitis B core antigen (anti‐HBc), the American Red Cross tested 107,473 voluntary blood donations for anti‐ HBc in 72 test sites during a 1‐week period. The system‐wide prevalence of anti‐HBc was 2.60 percent, with a range of 0.55 to 6.38 percent, depending on geographic region. For the American Red Cross, which collects approximately one‐half of the blood supply in the United States, excluding donated blood with anti‐HBc would result in a loss of approximately 159,500 units during the first year.