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Evidence for a ‘new’ Rh gene complex producing the rare C x (Rh9) antigen in the Somali population of East Africa
Author(s) -
Sistonen P.,
Abdulle O.A.,
Sahid M.
Publication year - 1987
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1987.27187121479.x
Subject(s) - antigen , phenotype , rh blood group system , gene , population , somali , biology , genetics , microbiology and biotechnology , medicine , antibody , linguistics , philosophy , environmental health
Four unrelated propositi with an unusual C x ‐positive Rh phenotype were found during a population survey of 513 Somalis. The Rh phenotypes of the propositi and their available relatives showed that the gene that produces the C x antigen differs from that found in whites in that it is inherited with an Rh gene complex that produces no C or D. Instead, this gene complex produced e s , c, and probably V, although it appeared that no f (ce) antigen was made. These findings suggest that C x cannot be considered a simple variant form of C but rather a distinct rare Rh antigen that may occur in association with different Rh gene complexes.