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Blood group incidence and Escherichia coli bacterial sepsis
Author(s) -
Wittels E. G.,
Lichtman H. C.
Publication year - 1986
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1986.26687043620.x
Subject(s) - sepsis , escherichia coli , incidence (geometry) , medicine , microbiology and biotechnology , biology , genetics , gene , physics , optics
Many strains of Escherichia coli possess an antigen that reacts with naturally occurring antibodies to human red cell B antigens. The authors tested the hypothesis that the presence of naturally occurring anti‐B isoagglutinins afford protection against the development of E. coli septicemia. The blood groups found in 115 patients with E. coli septicemia were compared with those found in three “control” populations: 138 patients with septicemia due to other organisms, 23,135 hospitalized patients, and 40,038 normal blood donors. The relative incidence of B and AB blood groups (not containing anti‐B antibodies) was significantly higher than A and O blood groups (containing anti‐B antibodies) in the group with E. coli septicemia. This finding supports the hypothesis.