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Hemolysis following intravenous immune globulin therapy
Author(s) -
Copelan E. A.,
Strohm P. L.,
Kennedy M. S.,
Tutschka P. J.
Publication year - 1986
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1986.26587020113.x
Subject(s) - hemolysis , medicine , globulin , immunology , immune system , antibody , gamma globulin , red cell
Two patients who had hemolysis after receiving large doses of intravenous immune serum globulin are reported. Both patients had positive direct antiglobulin tests due to alloantibodies contained in the immune serum globulin. Markedly increased red cell transfusion requirements and elevated serum bilirubin levels provided evidence of hemolysis.