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Uneventful plasma exchange with albumin replacement in a patient with a previous anaphylactoid reaction to albumin
Author(s) -
Edelman B. B.,
Straughn M. A.,
Getz P.,
Schwartz E.
Publication year - 1985
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1985.25586020118.x
Subject(s) - diphenhydramine , premedication , albumin , medicine , anaphylactoid reactions , anesthesia , anaphylaxis , egg albumin , serum albumin , human albumin , allergy , chemistry , immunology , chromatography , histamine
A patient who had a previous anaphylactoid reaction to albumin required plasma exchange for myasthenia gravis. She was rechallenged with albumin from a different manufacturer after premedication with diphenhydramine. No adverse reaction occurred during five exchanges over a 10‐day period. Possible pathogenic mechanisms and prevention of such reactions are discussed.