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Another example of the rare A y phenotype
Author(s) -
Drozda E. A.,
Dean J. D.
Publication year - 1985
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1985.25385219916.x
Subject(s) - abo blood group system , phenotype , saliva , genotype , antigen , immunology , gene , genotype phenotype distinction , microbiology and biotechnology , biology , genetics , chemistry , medicine
The red cells of a patient typed as group O, but her serum lacked anti‐ A. Upon further testing, it appeared that the ABO phenotype was A m . Saliva studies demonstrated a normal amount of H substance but reduced A substance. Family studies established the ABO genotype of the proposita as A 1 O. The results suggest that modification of the cellular and salivary expression of the A antigen in this patient was the result of a double dose of the modifier gene y , and that the ABO phenotype, while having characteristics similar to that of an A m , was actually A y .