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An unusual Donath‐Landsteiner antibody detectable at 37°C by the antiglobulin test
Author(s) -
Lindgren Sally,
Zimmerman Sherry,
Gibbs Frankie,
Garratty George
Publication year - 1985
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1985.25285169207.x
Subject(s) - autoantibody , immunology , medicine , antibody , coombs test
A 14‐year‐old boy with no history of transfusion experienced a hemolytic crisis attributed to paroxysmal cold hemoglobinuria. The Donath‐Landsteiner test was positive. The IgG autoantibody had anti‐P specificity but was unique in that it also reacted strongly by indirect antiglobulin test at 37 degrees C.