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Hemolysis following platelet transfusions from ABO‐incompatible donors
Author(s) -
Pierce R. N.,
Reich L. M.,
Mayer K.
Publication year - 1985
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1985.25185116506.x
Subject(s) - hemolysis , abo blood group system , titer , medicine , red cell , platelet , rh blood group system , group a , platelet transfusion , immunology , gastroenterology , antibody
Two hemolytic transfusion reactions related to isoagglutinins present in group O platelet concentrates are reported. The first, a severe reaction in a group A 10‐kg patient, resulted from transfusion of 200 ml of plasma containing a hemolytic anti‐A, titer 16, and an IgG anti‐ A, titer of 32,000. In the second case, a group B adult received between 50 and 70 ml of O plasma with a titer (16,000) of anti‐B. This was followed by hemolysis of approximately 40 percent of the patient's red cell volume.