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Altered blood group expression in a patient with congenital rubella infection
Author(s) -
Sherman L.A.,
Silberstein L.E.,
Berkman E.M.
Publication year - 1984
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1984.24384225037.x
Subject(s) - rubella , blood group antigens , medicine , congenital rubella , abo blood group system , antigen , immunology , malignancy , biology , andrology , measles , vaccination
An infant with probable congenital rubella infection developed altered blood group expression. This was noted at 4 months of age. The child's blood was typed on seven separate occasions during the first 8 weeks of life as type A, but on repeat testing, her cells failed to agglutinate with anti‐A and anti‐A,B typing serum. The A antigen was present, however, because an eluate made after incubating her red cells with anti‐A contained anti‐A, and A antigen was demonstrated on buccal mucosa cells. Altered expression of blood group A (loss of agglutinability) has occurred previously only in association with hematologic malignancy.