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Variant of type B blood in an El Salvador family. Expression of a variant B gene enhanced by the presence of an A2 gene
Author(s) -
Feng C.S.,
Cook J.L.,
Beattie K.M.,
Kao Y.S.,
Wallace M.E.,
Jongh D.S.
Publication year - 1984
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1984.24384225036.x
Subject(s) - genotype , gene , biology , phenotype , saliva , genetics , blood type (non human) , genotype phenotype distinction , gene family , gene expression , microbiology and biotechnology , abo blood group system , biochemistry
A variant of type B blood was found in three members of a family from El Salvador. In two members, both genotype BO, the blood and saliva had the characteristics of the phenotype Be1. In the third member, genotype A2B, the red cell B antigen was stronger than in his BO genotype relatives. Thus, in this family, the presence of the A2 gene appeared to enhance the expression of the B gene.