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Donor reaction to hydroxyethyl starch during granulocytap heresis
Author(s) -
DUTCHER J.P.,
AISNER J.,
HOGGE D. E.,
SCHIFFER C.A.
Publication year - 1984
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1984.24184122565.x
Subject(s) - hydroxyethyl starch , leukapheresis , premedication , medicine , intensive care medicine , surgery , anesthesia , biology , stem cell , cd34 , genetics
Granulocyte transfusion therapy has become relatively routine in centers treating patients with hematologic malignancies. The yield of granulocytes has been improved with newer leukapheresis techniques, premedication with corticosteroids, and the use of sedimenting agents, usually hydroxyethyl starch. Despite the relative safety of these techniques, there are risks to participating donors. A case of a donor reaction related to hydroxyethyl starch is presented. This report is a reminder that leukapheresis must be performed with careful consideration of therapeutic benefit‐to‐risk ratios.