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Acquisition of K: 1 ‐like antigen during terminal sepsis
Author(s) -
MCGINNISS M.H.,
MACLOWRY J.D.,
HOLLAND P.V.
Publication year - 1984
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1984.24184122557.x
Subject(s) - sepsis , microbiology and biotechnology , antigen , streptococcus , red cell , biology , immunology , bacteria , medicine , genetics
This report describes a patient whose own and transfused K:‐1 red cell populations became strongly K:1 during a terminal episode of sepsis due to a group D streptococcus organism, Streptococcus faecium. Subsequent in vitro studies using normal K:‐1 red cells inoculated with that organism showed that it could render the red cells agglutinable by reagents containing IgG anti‐K1. In addition, disrupted S. faecium organisms rendered Jkb‐negative red cells agglutinable by those reagents.