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Survival of Kn(a+)McC(a+) red cells in a patient with anti‐“Kn a /McC a ”
Author(s) -
Ballas S.K.,
Viggiano E.,
Draper E.K.
Publication year - 1984
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1984.24184122555.x
Subject(s) - antibody , in vivo , medicine , coombs test , transfusion reaction , blood transfusion , immunology , red blood cell , chemistry , biology , genetics
The in vivo survival of Kn(a+)McC(a+) red cells in a patient with anti‐ “Kna/McCa” was studied using 51Cr‐labeled incompatible cells. The antibody was IgG4, demonstrable at 37 degrees C in the antiglobulin test, and did not bind complement. Survival of tagged cells was 82.2 percent after 24 hours. The patient was transfused with a total of 29 units of incompatible blood with no evidence of ill effects. The direct antiglobulin test became positive after transfusion and remained positive for 2 1/2 months of observation. The findings suggest that individuals with anti‐ “Kna/McCa” may be transfused with Kn(a+)McC(a+) red cells.