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A “new” phenotype confirming a relationship between Cr a and Tc a
Author(s) -
LEVENE C.,
HAKEI N.,
LAVIE G.,
GKEENBEKG S.,
LAIRDFRYER B.,
DANIELS G.L.
Publication year - 1984
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1984.24184122551.x
Subject(s) - phenotype , antigen , antibody , microbiology and biotechnology , chemistry , biology , immunology , gene , biochemistry
The red cells of two sisters had very weak Cra and Tca antigens and reacted only weakly with the antibody of the Cr(a‐) Tc(a‐)person, Inab. Both sisters had an antibody, named anti‐Dra, to a high frequency antigen absent from their own cells and Inab cells but present on Cr(a‐) Tc(a+) and on Cr(a+) Tc(a‐) cells. This is the third example in which both Cra and Tca antigens are either absent or show weakened expression on the red cells, but the first case in which the unusual phenotype is shown to be inherited.