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Anti‐PP 1 P k and early abortion
Author(s) -
Cantin G.,
Lyonnais J.
Publication year - 1983
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1983.23483276877.x
Subject(s) - abortion , medicine , serology , phenotype , obstetrics , pregnancy , gynecology , first trimester , agglutination (biology) , andrology , gestation , immunology , biology , antibody , genetics , gene
Anti‐PP 1 P k is found in the serum of individuals of phenotype p. Recurrent first trimester miscarriages have been reported in nearly 50 percent of mothers with the p phenotype. A comparative serologic study of three p phenotype mothers is reported. The proposita had three miscarriages while her two identical twin sisters had normal pregnancies. Following serum fractionation on DEAE‐cellulose, serial agglutination with P 1 and P 2 erythrocytes indicated a possible association between IgG anti‐P and the increased risk of abortion.