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A slide test for detecting neutrophil‐associated complement components
Author(s) -
Harmon D. C.,
Weitzman S. A.,
Stossel T. P.
Publication year - 1983
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1983.23283172850.x
Subject(s) - neutropenia , complement (music) , immunology , complement system , antiserum , immune system , medicine , complement component 5 , innate immune system , antibody , biology , gene , phenotype , biochemistry , toxicity , complementation
Complement components deposited on neutrophils were detected by a new test that uses staphylococcal protein A and antisera against complement. Serum from three of 51 patients thought to have immune neutropenia deposited complement but not IgG on their own and normal neutrophils. Some cases of immune neutropenia may be caused primarily by complement‐mediated neutrophil destruction.