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The biochemical effects of CPDA‐2‐drawn red blood cells of delayed refrigeration prior to component preparation
Author(s) -
Moore G.L.,
Ledford M.E.,
Merydith A.
Publication year - 1982
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1982.22683068608.x
Subject(s) - blood preservation , medicine , adenosine triphosphate , platelet , chemistry , andrology
The effects of an 8‐hour hold at 22 degrees C prior to component preparation were evaluated in a split‐bag study using nine units of blood preserved in citrate‐phosphate‐dextrose‐adenine (CPDA‐2). Each unit was divided in half, platelet‐rich plasma removed at 0 or 8 hours, respectively, and the half units of red blood cells stored at 4 degrees C for 42 days. The only red blood cell metabolic differences seen in the bags held 8 hours (compared to those not held) were a 21 percent rise in adenosine triphosphate, which was not significant after 14 days of storage, and a 33 percent loss of 2,3‐diphosphoglycerate which resulted in a loss curve similar to that seen with acid‐citrate‐ dextrose blood. The logistic advantages seem to warrant an 8‐hour holding period for red blood cells drawn in CPDA‐2.