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Platelet washing with a blood cell processor
Author(s) -
Kalmin N. D.,
Brown Deborah J.
Publication year - 1982
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1982.22282177118.x
Subject(s) - platelet , saline , blood cell , platelet transfusion , medicine , whole blood , chromatography , surgery , chemistry , andrology , immunology , anesthesia
Washing of platelet components for transfusion may be indicated in selected patients. This study was designed to determine a protocol using an automated cell processor to remove plasma proteins from pooled platelet concentrates, stored at 20 to 24 degrees C with constant rotation. A 1500‐ml, 0.9% saline‐wash procedure is described. Eight percent of the platelets were lost with the procedure (range, 0–19%), while a mean of 99.6 percent of the plasma protein was removed (range, 99.2‐99.8%). The clinical effectiveness of maternal platelets washed by this method was demonstrated in a case of alloimmune neonatal thrombocytopenia.