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Rh immune globulin and the Rh‐positive D u variant, mother
Author(s) -
Konugres A.A.,
Polesky H.F.,
Walker R.H.
Publication year - 1982
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1982.22182154227.x
Subject(s) - immune system , medicine , rh blood group system , rh isoimmunization , antibody , pregnancy , globulin , immunology , obstetrics , fetus , physiology , biology , genetics
Questions have been raised by statements of the American College of Obstetricians and Gynecologists that Rh immune globulin should be given to all Rh positive, Du variant, mothers who have recently delivered Rh positive infants. This practice is not recommended. However, blood banks must assure that a positive Du test on a mother's blood sample is not caused by a massive fetal‐maternal hemorrhage. Failure to recognize this cause of a positive Du test may result in the administration of an inadequate dose of Rh immune globulin.